معرفی
Massimo Loda is a Professor and Chair of Pathology and Laboratory Medicine at Weill Cornell Medical College, with a distinguished career in prostate cancer research, cancer metabolism, and molecular pathology. His work spans mechanistic studies, therapeutic development, and translational applications in oncology and tumor microenvironment biology.
- Primary Affiliation: Weill Cornell Medical College, Pathology and Laboratory Medicine
- Research Focus: Prostate cancer pathogenesis, lipid metabolism, androgen receptor signaling, genomic instability, and tumor microenvironment dynamics
Recent publications (2024-2025) highlight his work on metabolic vulnerabilities (FASN/ACCA inhibition), stromal-tumor interactions, deep learning pathology analysis, and mitochondrial targeting in prostate cancer. His studies bridge genomics, metabolomics, and computational pathology to identify therapeutic strategies and biomarkers.
Key trends in his research include:
- Lipid metabolism as a therapeutic axis in hormone-sensitive and castration-resistant disease
- Machine learning applications for tumor classification and microenvironment analysis
- Stromal component characterization in lethal prostate cancer
- Enzyme-targeted therapies (CDK12, O-GlcNAc transferase)
His work consistently addresses prostate cancer disparities (African ancestry studies), metastatic mechanisms, and precision medicine approaches through genomic and proteomic profiling.
