Masahiro Onoguchi

Masahiro Onoguchi is a Researcher at the Faculty of Science and Engineering of Waseda University since 2025. He previously held positions at Waseda University (2021-2025), National Institute of Advanced Industrial Science and Technology (2018-2021), Keio University School of Medicine (2016-2018), Stanford University School of Medicine (2013-2014), and the University of Tokyo (2010-2013). He earned a PhD in Life Sciences from the University of Tokyo.

Research Interests: Onoguchi focuses on

• RNA-protein interactions
• Functional noncoding RNA
• Genome evolution
• Neurogenesis
• Transposon biology
• Enhancer elements
• Long noncoding RNA (lncRNA) regulation

His work integrates genomics, molecular biology, and bioinformatics to explore how transposable elements contribute to gene regulatory networks in the brain and RNA-mediated chromatin control.

Scientific Awards:

• Overseas Study Grant Postdoctoral Fellowship from Uehara Memorial Foundation
• Doctoral Thesis Special Encouragement Award at University of Tokyo Graduate School of Frontier Sciences
• Dean's Award at University of Tokyo Graduate School of Frontier Sciences

Research Trends: His publications highlight the role of transposons in brain-specific gene regulation, functional RNA elements derived from repetitive sequences, and the interplay between RNA biology and chromatin dynamics. Projects funded by JSPS and JST reflect his interdisciplinary approach to noncoding RNA functions in neurodevelopment and biomedical applications.

Research Projects: He has led grants including

• Development of comprehensive analysis technology for RNA functional domains (JSPS, 2025-2028)
• Systematic understanding of RNA-centric molecular networks in biological phase separation (JSPS, 2023-2026)
• Novel RNA-protein complex analysis for drug discovery (JST, 2024-2025)