معرفی
Mary Galinski is a Professor in the Hubert Department of Global Health at Emory University's School of Medicine. Her research focuses on malaria pathogenesis, vaccine development, and host-parasite interactions using non-human primate models. She has contributed extensively to understanding Plasmodium species biology, particularly Plasmodium vivax and Plasmodium knowlesi, through proteomics, transcriptomics, and systems biology approaches.
Her work emphasizes antigenic variation mechanisms, immune response dynamics, and the application of genomic technologies to study malaria lifecycle stages. Notable contributions include defining SICAvar protein roles in cytoadhesion and identifying biomarkers for vaccine development. She collaborates on projects involving drug repurposing and systems biology frameworks to address malaria complexity.
Galinski's research integrates metabolomics, transcriptomics, and proteomics data to uncover host-pathogen relationships. Her lab employs cutting-edge methods like single-molecule genome sequencing and Bayesian network modeling to dissect malaria infection dynamics. Recent studies explore microbiome disruptions during malaria and the immunological basis of clinical tolerance in infections.
Her publications highlight translational research bridging basic science and public health, with a focus on vivax malaria's unique challenges such as relapsing infections and hypnozoite dormancy. She advocates for non-human primate models as critical tools for studying malaria's systemic effects and vaccine efficacy.
