Martial Toffano

Martial Toffano is a Researcher (Chargé de Recherche) at the Laboratoire de Chimie Moléculaire (LCM) within the Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO) at Université Paris-Saclay. His work focuses on organocatalysis, asymmetric synthesis, phosphonate chemistry, and green catalytic processes. Key projects include developing novel organocatalysts (e.g., Fiaud’s Acid, 2-hydroxymethyl-18-crown-6), enzymatic kinetic resolution protocols, and bio-inspired catalysts derived from biomass.

Research Interests:

• Design of chiral catalysts for enantioselective transformations
• Organocatalytic cascade reactions
• Phosphonate synthesis with biological applications
• Lipase-catalyzed promiscuity in novel bond formations
• Development of eco-friendly synthetic methods

Publications Trends: Recent studies emphasize:

• Triple cascade organocatalysis for bis-lactone synthesis (2024)
• Enantioselective deacylation via CAL-B lipase (2021-2023)
• Computational studies (DFT/molecular docking) for drug-target interactions (2023)
• Novel phospholane oxides and spiro-dihydropyranones (2020-2024)

Advising & Grants: Collaborations span medicinal chemistry, sustainable catalysis, and materials science. Active in training researchers through ICMMO’s doctoral programs.

Labs & Teams: Part of the LCM team specializing in molecular catalysis and biomass valorization.