معرفی
Marta Buzzetti serves as a Postdoctoral Researcher (Research Fellow) at the Centre for Tumour Biology under the supervision of Professor Marco Gerlinger. Her work investigates tumor-intrinsic mechanisms driving resistance to CD3 bispecific antibodies in colorectal cancer through advanced molecular techniques.
Her research spans Cancer Immunology, Immunotherapy, Therapy Resistance, and Colorectal Cancer, utilizing patient-derived organoid co-cultures and genome-wide CRISPR screens to identify critical gene networks. This approach aims to uncover novel therapeutic targets to overcome immunotherapy resistance, with potential applications across multiple cancer types. Dr. Buzzetti's methodology bridges translational oncology and functional genomics to address clinical treatment failures.
