معرفی
Dr Mark Toshner is an Associate Professor of Respiratory Medicine at the University of Cambridge's Victor Phillip Dahdaleh Heart & Lung Research Institute. He serves as Director of the NIHR Clinical Research Facility and maintains an honorary consultant role at Royal Papworth Hospital specializing in pulmonary vascular disease. His work bridges clinical practice with translational research through the national UniPHy network.
- Established blood-derived endothelial cell approach for PAH research
- Pioneered adaptive/decentralized clinical trial methodologies
- Developed digital endpoints for remote PH monitoring
- Co-investigator in therapies achieving marketing authorization
Current projects focus on:
- StratosPHere 1 & 2 - Biomarker validation for BMPR2-targeted therapies
- Cohort Digital - Minimally-invasive patient follow-up
- HEAL-COVID - Decentralized platform trials for post-COVID care
Scientific contributors:
- British Heart Foundation (BHF) Training Fellowship
- Wellcome/NIHR Lecturership
- MRC DPFS funding
- NIHR HTA & BHF grants
- Co-investigator in 22 phase 2-3 clinical trials
He leads the world's first decentralized therapeutic platform trial for post-COVID recovery and develops open-source tools for risk prediction in pulmonary endarterectomy. Collaborators include Professor Charlotte Summers, Dr Chris Wallace, and Professor Eoin McKinney.
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