معرفی
Mark J. Uline serves as Professor and Chair of the Biomedical Engineering Department at the University of South Carolina's Molinaroli College of Engineering and Computing, with affiliate status in Chemical Engineering. His academic career at USC spans over 14 years, progressing from Assistant Professor (2011) to current Chair (2025-present), following leadership roles as Program Director (2021-2024) and Undergraduate Director (2014-2021).
Education
- Ph.D. in Chemical Engineering, Purdue University (2008)
- B.S. in Chemical Engineering, Purdue University (2003)
- Postdoctoral Associate, Biomedical Engineering, Northwestern University (2008-2011)
Research Focus Dr. Uline's computational biophysics research investigates fundamental interactions at biological interfaces through molecular modeling. His group specializes in lipid bilayer phase transitions, surfactant-driven nematic ordering in liquid-crystal films, bubble/droplet nucleation theory, and molecular dynamics simulations in the isothermal-isobaric ensemble. Current work emphasizes nanomedicine applications including nanoparticle-biomembrane interactions and GPCR spatial organization in plasma membranes, with significant implications for drug delivery and cardiovascular therapies. His methodology integrates self-consistent field theory with advanced simulation techniques to address complex biomolecular phenomena.
Publication Trends Analysis of Dr. Uline's 15 most recent publications (2023-2025) reveals a strategic evolution from foundational thermodynamics toward applied nanomedicine. Over 60% of recent work focuses on GPCR membrane organization and cardiovascular interventions, particularly drug-coated balloon technology. His research consistently bridges computational biophysics with clinical applications, demonstrating increasing collaboration between molecular modeling and translational biomedical engineering. The persistent thread remains understanding interfacial phenomena through rigorous computational approaches.
Teaching & Leadership Dr. Uline teaches core courses including BMEN 240 (Cellular and Molecular Biology), BMEN 290 (Thermodynamics of Biomolecular Systems), and graduate-level modeling courses. As Department Chair, he oversees academic programs while maintaining active research leadership through the Uline Research Group, which operates at the intersection of chemical engineering principles and biomedical challenges.
