معرفی
Dr. Mark E. Samuels is an Associate Professor in the Department of Medicine at the Faculty of Medicine, Université de Montréal. He is affiliated with the Centre de recherche Azrieli du CHU Sainte-Justine and the Centre hospitalier universitaire Sainte-Justine (CHU Sainte-Justine).
Dr. Samuels received his A.B. degree summa cum laude in Molecular Biology from Princeton University and his Ph.D. in Biology from the Massachusetts Institute of Technology where he worked in the laboratory of Prof. Phillip Sharp. His academic career spans over 20 years of research in molecular mechanisms of cellular function and development.
His research focuses on human molecular genomics, particularly the characterization of rare monogenic disorders using traditional marker-assisted linkage mapping or next-generation sequencing. His work has led to the discovery of twenty genes involved in eye development, neuronal function, growth, endocrinology, and iron metabolism. His laboratory studies the functions of the genes identified in the course of human genomic analysis.
His publication record shows a strong focus on genetic disorders, with research spanning from basic gene expression and sex-determination in fruit flies to human disease genetics. His more recent work emphasizes next-generation sequencing approaches to identify genetic mutations underlying rare disorders.
- Presidential Scholar in the United States in 1975
Dr. Samuels has supervised multiple graduate students across various programs including Biochemistry and Molecular Medicine, Biomedical Sciences, Molecular Genetics, and Applied Biotechnology. He has secured research funding from multiple sources including IRSC, Genome Atlantic, and the GO Foundation. His research projects span areas such as congenital hypothyroidism, Ehlers-Danlos syndrome, orphan diseases, and cardiac malformations.
His laboratory at the Centre de recherche Azrieli du CHU Sainte-Justine is part of a collaborative network that includes researchers from across Quebec and Canada.
