Mariusz Karbowski

Dr. Mariusz Karbowski is an Associate Professor in the Department of Biochemistry and Molecular Biology at the University of Maryland School of Pharmacy. His research focuses on mitochondrial membrane dynamics, ubiquitin-proteasome system regulation of mitochondria, and mitochondrial quality control mechanisms. He holds a Ph.D. from Nagoya University School of Medicine and completed postdoctoral training at the NIH. Dr. Karbowski has authored over 70 peer-reviewed publications with ~6,000 citations, emphasizing mitochondrial fusion/fission regulation, mitochondrial-actin interactions, and apoptotic pathways.

Research Interests:
- Ubiquitin-dependent signaling in mitochondrial function
- Mitochondrial fusion/fission regulation
- Mitochondrial-actin crosstalk
- Proteasome-mediated mitochondrial protein turnover
- Development of live-cell imaging tools for mitochondrial analysis

Selected Article Trends:
Recent work explores mitochondrial dynamics in congenital heart defects, peroxisome biogenesis, and cardiomyocyte signaling. Key themes include MARCH5 ubiquitin ligase function, Drp1-mediated fission, and mitochondrial autophagy mechanisms.

Awards and Recognition:
No specific awards listed in provided materials.

Advising and Grants:
No student advisees explicitly listed. Research supported by NIH grants and institutional funding.

Labs/Teams:
Leads the Karbowski Lab at UMD School of Pharmacy, focusing on mitochondrial molecular mechanisms.