Mario Jolicoeur

Mario Jolicoeur is a Full Professor in the Department of Chemical Engineering at Polytechnique Montréal. His research focuses on metabolic engineering, biomedical applications, and bioreactor design. He is affiliated with Spheroid AI Inc. (Co-founder, Scientific Director), Viridios (Collaborating Researcher), and the Institute of Biomedical Engineering (Member).

• Education: B.Sc.A., M.Sc.A., Ph.D. (Polytechnique Montréal and Paul-Sabatier University, Toulouse), Visiting Engineer (MIT)

Jolicoeur develops metabolic engineering tools for cancer therapies and therapeutic agent production, designs mathematical models for cellular metabolism regulation, and creates aseptic culture equipment for diverse cells. His work spans CHO cells, microalgae, and tissue engineering.

Recent publications highlight metabolic therapies for ovarian cancer, dynamic modeling of CHO cultures, and lipid production in Chlorella. Trends include cancer metabolism, mitochondrial dynamics, and bioreactor optimization.

Supervision: He has mentored 43 graduate students since 1990, including those working on metabolic models, bioreactors, and biotherapies. Notable projects involve methylene blue in cancer treatment, ABE fermentation, and chondrocyte culture systems.

Labs & Teams: Collaborates with interdisciplinary groups in biomedical engineering and chemical engineering, utilizing advanced bioreactor platforms and computational models.