Mariano Martín Gomez

Mariano Martín Gomez is a researcher at the Institute for Bioengineering of Catalonia (IBEC), affiliated with the research group "Protein Phase Transitions in Health and Disease". His work focuses on understanding the molecular mechanisms underlying protein misfolding and aggregation, particularly in the context of neurodegenerative diseases and amyloid formation.

Research Focus: His primary research interests lie in protein phase transitions, amyloid formation, and the molecular triggers that lead to pathological protein aggregation. He employs a multidisciplinary approach combining massive mutagenesis, deep learning, and experimental quantification to uncover the structural and functional determinants of protein behavior.

Recent Work: His 2025 publications in PNAS, Science Advances, and Nature Communications demonstrate a strong trajectory in integrating wet-lab experimentation with computational modeling to study protein aggregation and its implications in disease. These works span from amyloid motif discovery in Bri2 to large-scale mapping of MCT8 variants affecting thyroid hormone transport.