Marianela Jordan

Marianela Jordan is a Clinical Assistant Professor of Pediatrics at the University of Southern California, focused on cardiovascular research with a clinician-educator role. Her work integrates molecular mechanisms, genetic models, and translational medicine to address heart disease pathophysiology.

Research interests include electronic cigarette-induced cardiotoxicity, genetic disorders like Huntington’s and muscular dystrophy, diabetes-related cardiomyopathy, and novel therapeutic interventions. She employs advanced techniques such as optogenetics, viral vectors, and nanomedicine for preclinical studies.

Her publications (2002–2023) highlight expertise in cardiac dysfunction mechanisms, including studies on sodium-calcium exchangers, mitochondrial signaling, and biomaterial-based therapies. Key themes include understanding how environmental exposures (e.g., e-cigarettes), genetic mutations, and metabolic disorders impact heart function.

Notable contributions include demonstrating e-cigarette-induced cardiac remodeling in obese mice and developing Zn2+-releasing phage nanoparticles for wound infection treatment. Her work bridges basic science and clinical applications, with potential implications for public health and personalized medicine.

Grants and lab collaborations are not explicitly detailed in the provided text, though her extensive publication record suggests involvement in NIH-funded or industry partnerships. Education background and formal training details are not included here.