معرفی
Mariana Angoa-Perez serves as Assistant Professor in the Department of Physiology at Wayne State University, conducting interdisciplinary research at the intersection of neuroscience, neurotoxicology, and gut-brain axis interactions with emphasis on neuropathological mechanisms.
Her academic credentials include:
- B.S. in Biology, Autonomous University of Puebla, Mexico (2003)
- Ph.D. in Biomedical Sciences, National Autonomous University of Mexico (2007)
- Post Doctoral Fellow in Psychiatry and Behavioural Neurosciences, Wayne State University (2008-2011)
- Visiting Research Fellow, Henry Ford Health System, William T Gossett Neurology Laboratories (2004-2005)
Dr. Angoa-Perez's research program integrates animal behavior, molecular neurochemistry, and bioinformatics to investigate neurotoxic effects of environmental agents (ozone, nerve agents, substituted amphetamines) on monoamine systems, with recent emphasis on gut microbiome influences in Gulf War Illness, traumatic brain injury, and substance use disorders. Her methodological expertise spans histopathology, 16S rRNA sequencing, and behavioral assessments for anxiety, depression, and psychostimulant responses.
Publication analysis reveals a strategic research evolution from classical neurotoxicology (2018-2019 cathinone studies) toward contemporary microbiome-neurology interfaces (2020-2021 Gulf War Illness and TBI models), demonstrating consistent application of transgenic models (TPH2 knockouts) and multi-omics approaches. Current work focuses on bidirectional gut-brain communication pathways in neuropathology using high-fat diet interventions and neurotoxin exposure paradigms.
