معرفی
Dr. Maria Jimenez-Sanchez is a Senior Lecturer in Cellular and Molecular Neurodegeneration at King's College London, affiliated with the Department of Basic and Clinical Neuroscience within the School of Neuroscience. Her research focuses on understanding the role of molecular chaperones and autophagy in astrocytes and their implications in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. She leads the Jimenez-Sanchez Lab, which investigates mechanisms preventing protein misfolding and accumulation, with particular emphasis on astrocyte-neuron communication and glial cell dysfunction.
Her work is funded by grants including the MRC Transition Support Award and Alzheimer’s Research UK projects. Key collaborations include partnerships with researchers like Dr. Wendy Noble, Professor Diane Hanger, and Dr. Beatriz Gomez Perez-Nievas. Dr. Jimenez-Sanchez’s contributions span over 30 publications, with recent studies highlighting astrocytic HSPB1 secretion for neuroprotection, truncated tau’s impact on autophagy, and microglial CCR5 signaling in neurodegeneration.
Awards include the MRC Career Development Award and recognition for innovative approaches in neurodegenerative disease research. Her lab’s findings bridge basic science and translational medicine, emphasizing the therapeutic potential of targeting glial autophagy and molecular chaperones.
