Maria Dall'Era

Maria Dall'Era, MD is the Jean S. Engleman Distinguished Professor of Medicine and Chief of the Division of Rheumatology at the University of California, San Francisco (UCSF). She also serves as Director of the UCSF Rheumatology Clinical Research Center and Co-director of the UCSF Lupus Clinic. Her clinical and research focus centers on systemic lupus erythematosus (SLE) and lupus nephritis, with expertise in developing novel therapies and studying epidemiology and outcomes of lupus patients.

Education:

• BA in Immunology, University of California, Berkeley, 1993
• M.D., University of California, San Francisco School of Medicine, 1997
• Residency in Internal Medicine, University of California, San Francisco
• Fellowship in Rheumatology, University of California, San Francisco, 2004

Dr. Dall'Era's research interests span multiple dimensions of lupus care and management. She investigates treatment optimization for lupus nephritis, epidemiological patterns of disease manifestation across diverse populations, and the development of novel therapeutic approaches. Her work emphasizes health disparities, particularly examining how race, ethnicity, and socioeconomic factors influence lupus outcomes. She has pioneered research on the relationship between physical activity, stress, and disease activity in lupus patients, and has contributed significantly to understanding epigenetic and molecular mechanisms underlying disease heterogeneity.

Analysis of her recent publication record reveals a strong focus on precision medicine approaches to lupus management, with particular attention to biomarker discovery, treatment response prediction, and addressing health disparities. Her work spans basic science investigations into molecular mechanisms of disease through to large-scale clinical studies and guideline development. The interdisciplinary nature of her research connects immunology, genomics, epidemiology, and patient-centered outcomes research.

Scientific Awards:

• Evelyn V. Hess Award, Lupus Foundation of America, 2023
• Edmund L. Dubois Memorial Lectureship Award, American College of Rheumatology, 2018
• Purple Ribbon Award, Lupus Foundation of America, 2014
• Exceptional Physician Award, UCSF, 2010
• Ira M. Goldstein Award for Outstanding Teaching in Rheumatology, UCSF, 2007
• Ephraim Engleman Award for Excellence in Arthritis Research, UCSF, 2006

Dr. Dall'Era serves as Principal Investigator for the CDC-funded California Lupus Epidemiology Study, a population-based longitudinal lupus cohort in the San Francisco Bay Area. She also leads multiple clinical trials focused on SLE and lupus nephritis. Her leadership extends to national organizations where she serves as Co-Chair of the Lupus Therapeutics Board of Directors, Co-Chair of the LRA's Lupus Industry Council, and member of the Lupus Accelerating Breakthroughs Consortium Research Committee. She is actively involved in developing the American College of Rheumatology's Guidelines for the Treatment of SLE and lupus nephritis.

Her laboratory and research team work within the UCSF Rheumatology Clinical Research Center, collaborating with the Accelerating Medicines Partnership RA/SLE Network and other multidisciplinary teams to advance understanding of lupus pathogenesis and treatment. The team employs approaches ranging from single-cell analysis and epigenetic studies to large-scale epidemiological investigations and clinical trials.