Marco Mielcarek

Dr. Marco Mielcarek is a distinguished Professor in the Clinical Research Division at Fred Hutch Cancer Center and the Division of Hematology and Oncology at the University of Washington. He serves as Medical Director of the Adult Blood and Marrow Transplant Program at Fred Hutch Cancer Center, where he focuses on improving clinical care and integrating cutting-edge research with patient experience. His clinical practice spans Fred Hutch Cancer Center - South Lake Union and UW Medical Center - Montlake.

Dr. Mielcarek's research interests center on graft-versus-host disease (GVHD), a potentially life-threatening complication where transplanted donor cells attack the patient's body. His work explores prevention and treatment strategies for GVHD with minimal toxicity, including the innovative use of high-dose cyclophosphamide infusions to safely prevent GVHD after blood stem cell transplantation. His recent publications demonstrate expertise in hematopoietic cell transplantation, immune reconstitution, viral infections post-transplant, and pandemic response in transplantation settings.

His research trends show a consistent focus on improving outcomes in blood and marrow transplantation, with recent emphasis on standardizing definitions in transplantation medicine, managing viral infections, and adapting transplant protocols during the COVID-19 pandemic. His work bridges basic science with direct clinical applications that enhance patient care in the field.

Dr. Mielcarek has made significant contributions to clinical guidelines, including the NCCN Guidelines for Hematopoietic Cell Transplantation, reflecting his leadership in establishing standards for transplantation practices.

As Medical Director of the Adult Blood and Marrow Transplant Program, he oversees one of the leading transplantation centers, integrating clinical care with research initiatives that advance the field. His work with the Seattle research community has produced important insights on managing transplantation during public health emergencies.