Marco Casarotto

Marco Casarotto is an Associate Professor in the Division of Biomedical Science and Biochemistry within the Research School of Biology at the Australian National University. He serves as Group Leader of the Casarotto Group - Biomolecular Interactions and maintains an active research program with publications spanning molecular biology, biochemistry, and cellular physiology.

His primary research interests focus on protein-protein interactions with particular emphasis on calcium signaling pathways, ryanodine receptor channels, and IRF4 in immunological contexts. His work bridges fundamental molecular mechanisms with clinical applications in cardiac physiology, cancer biology, and immunology. His research demonstrates how molecular interactions regulate cellular processes in both health and disease states.

Casarotto's publication record reveals consistent research output with significant contributions to understanding the structural and functional aspects of protein complexes. His recent work shows an increasing focus on the role of IRF4 in lymphoma and immunodeficiency, alongside continued investigation of calcium signaling mechanisms in muscle physiology. His research demonstrates interdisciplinary connections between structural biology, cellular physiology, and disease mechanisms.

His current research activities include leading the Casarotto Group and collaborating on multiple projects including 'Pursuing IRF4 as a therapeutic opportunity for lymphoid malignancies' (2022-2025) and 'Enhanced high-field nuclear magnetic resonance spectroscopy' (2022). His work receives consistent citations, with a reported h-index of 24 based on Scopus data.

His laboratory focuses on biomolecular interactions using techniques including structural biology, protein biochemistry, and cellular physiology approaches to investigate fundamental mechanisms underlying human diseases.