Marc Samsky

Marc Samsky, MD is an Assistant Professor in the Department of Cardiovascular Medicine at Yale School of Medicine. His clinical focus is on heart failure care, with academic interests in improving evidence-based therapy use, novel treatments for hospitalized patients, and optimizing mechanical circulatory devices for end-stage heart failure. He holds board certifications in Advanced Heart Failure & Transplant Cardiology and Internal Medicine.

• Education:
  • MD, Duke University School of Medicine (2013)
  • BS Biology, Duke University (2009)
• Fellowships/Residencies:
  • Advanced Heart Failure & Cardiac Transplantation, Duke University (2022)
  • Cardiovascular Medicine Fellowships, Duke University (2021, 2017)
  • Chief Medical Resident, Duke University (2018)

His research focuses on cardiogenic shock management, mechanical circulatory support devices, and improving heart failure outcomes through EHR strategies. He co-leads the American Heart Association Cardiogenic Shock Registry and contributes to international clinical guidelines through organizations like SCAI and ACC.

Key research themes include:

• Development of standardized shock management protocols
• Impact of frailty on shock outcomes
• Cardiohepatic syndrome in critical care settings
• Optimizing sodium-glucose cotransporter 2 inhibitor use

He serves as Associate Editor for Heart Failure Reviews and participates in professional activities with the American College of Cardiology. His work bridges clinical care innovation with translational research to address unmet needs in advanced heart disease.