Manish B. Shah

Manish B. Shah is an Associate Professor in the Department of Pharmaceutical Sciences at Albany College of Pharmacy and Health Sciences (ACPHS). He specializes in structural biology and drug metabolism, with a focus on Cytochrome P450 enzymes (CYP2C8, CYP2C9, and CYP2U1). His research explores genetic polymorphisms' impact on drug metabolism and pharmacogenomic applications. Dr. Shah holds a PhD from the University of Nottingham, UK, and has held postdoctoral positions at institutions including UC San Diego and the University at Buffalo.

Education:

• PhD, University of Nottingham, UK
• MSc, University of Nottingham, UK
• BPharm, Karnatak University, India

Research Interests:
Dr. Shah's work centers on understanding enzyme structure-function relationships, particularly in CYP enzymes. He investigates genetic variations' effects on drug metabolism efficiency and explores ligand binding mechanisms using X-ray crystallography and molecular modeling. His studies aim to improve personalized medicine through pharmacogenomic insights.

Awards and Recognition:

• Best Abstract Award (ASPET 2012)
• Invited Reviewer for American Heart Association grants (2024)
• Councilor, ASPET Drug Metabolism Division (2020–2023)
• NIH MSFA Study Section Reviewer (2020)

Professional Contributions:

• Judged student/postdoc research at major conferences (2020, 2013)
• Member: American Society for Pharmacology and Experimental Therapeutics, American Heart Association

Labs/Teams: Leads a research group focused on structural enzymology and pharmacogenomics at ACPHS. His lab employs advanced biophysical techniques to study enzyme-drug interactions.