Magnus Alphey

Magnus Alphey is a Researcher at the Biomedical Sciences Research Complex, University of St Andrews. His work focuses on structural and functional analysis of enzymes critical to metabolic and DNA replication processes, particularly ATP phosphoribosyltransferase and DNA polymerase systems.

• Current projects involve drug discovery for Alzheimer's disease and cancer
• Expertise in X-ray crystallography and enzymatic kinetic analysis
• Active collaborations include structural biology teams across Europe

Research spans Biochemistry, Molecular Biology, and Medical Research, with specific subfields covering protein dynamics, allosteric regulation, DNA repair mechanisms, and neurodegenerative therapies. Recent publications demonstrate leadership in high-throughput screening and structural characterization of disease-relevant enzymes.

Dataset contributions to Protein Data Bank and Zenodo archives include structural models of ATP phosphoribosyltransferase variants and PCNA complexes, forming a unique fingerprint in topics like Adenosine Triphosphate (100%), Phosphoribosyltransferase (100%), and Protein Motifs (66%).