MOK YU-KEUNG HENRY

Yu Keung Mok serves as Associate Professor and Deputy Head of the Department of Biological Sciences at the National University of Singapore (NUS). His research group employs Nuclear Magnetic Resonance (NMR) spectroscopy and X-ray crystallography to elucidate the structure-function relationships of proteins implicated in human diseases, with a focus on allergens and bacterial pathogenesis mechanisms.

Dr. Mok's primary research areas include:

• Structural characterization of dust mite and cockroach allergens (e.g., Blo t 5, Blo t 21, Der f 7) to map IgE epitopes and understand their role in asthma and atopic dermatitis;
• Investigation of bacterial type III and VI secretion systems, particularly the structural analysis of chaperone-translocator complexes and their regulation by two-component systems (PhoP/PhoQ) in response to environmental cues.

His recent publications (2010-2025) demonstrate a strong emphasis on structural biology approaches to study host-pathogen interactions, including dengue virus pathogenesis, bacterial secretion mechanisms, and allergen immunology. The work integrates protein engineering, binding assays, and structural data to inform therapeutic design.

Scientific Awards:

• No major scientific awards were mentioned in the provided text.

Dr. Mok's laboratory operates within the Department of Biological Sciences at NUS, utilizing advanced structural biology facilities. His research involves interdisciplinary collaborations with experts in microbiology, immunology, and biochemistry, as reflected in his extensive publication record.