معرفی
M. Elizabeth Deerhake is an Associate Research Scientist in the Department of Neurology at the Yale School of Medicine, Yale University. Her research focuses on immunology and neuroinflammation, particularly exploring the role of Dectin-1 signaling in autoimmune diseases and CNS pathophysiology. She holds a PhD in Immunology from Duke University (2022), an MD from Duke University (2022), and a BS in Molecular, Cellular, and Developmental Biology from Yale University (2012). Her work has been published in high-impact journals such as Immunity, Journal of Immunology, and Neurology.
Dr. Deerhake’s research interests include the mechanisms of autoimmune neuroinflammation, inflammasome activation in astrocytes, and the interplay between immune cells and the central nervous system. She collaborates with researchers like Kaelyn Sumigray and Tian Chi on projects addressing PD-L1 regulation, ROS-mediated suppression of T cells, and the role of osteopontin in graft-versus-host disease.
Her recent publications highlight advancements in understanding Dectin-1’s non-canonical pathways in limiting CNS autoimmunity and the functional heterogeneity of immune cells like neutrophils and macrophages in disease contexts. This work contributes to translational research aimed at developing therapies for autoimmune and inflammatory disorders.
