Lucy Stead

Dr. Lucy Stead is an Associate Professor at the School of Medicine, University of Leeds. She is a computational cancer biologist specializing in neuro-oncology, cancer genomics, and transcriptomics, with a focus on glioblastoma multiforme (GBM) and intratumour heterogeneity (ITH). Her research integrates high-throughput sequencing, in silico modeling, and functional genomics to study treatment resistance in brain cancer.

• Areas of Expertise: Neuro-Oncology, Cancer Genomics, Computational Biology
• Key Responsibilities: UKRI Future Leaders Fellow, Head of Glioma Genomics Module

Her work investigates how genomic and transcriptomic heterogeneity in GBM contributes to tumor recurrence, using patient-matched pre-treatment and recurrence samples. Computational and experimental approaches are combined to validate subclone dynamics and treatment-resistance mechanisms.

Dr. Stead is affiliated with the Leeds Institute of Medical Research at St James's, Brain Cancer Research Group, and serves on the Scientific Advisory Board of The Brain Tumour Charity and the Leeds Cancer Research Centre Executive Committee.

• Scientific Awards: UKRI Future Leaders Fellow

She supervises postgraduate researchers including Muna Al-Jabri, Rhiannon Barrow, and Nazia Ahmed, and contributes to education through module leadership (MEDM5101). Her work emphasizes interdisciplinary collaboration to address challenges in brain cancer evolution and therapy.