معرفی
Lucia Banci is a Full Professor of Chemistry at the University of Florence, affiliated with the Magnetic Resonance Center (CERM) and the Department of Chemistry. She pioneered the in-cell NMR technique to study proteins in living human cells, enabling atomic-resolution insights into biological processes. Her research focuses on structural biology, metal-ion biology, and structural vaccinology, with groundbreaking contributions to understanding iron-sulfur protein biogenesis and vaccine design.
Leadership Roles:
- Founder and former Director of CERM
- Head of the Italian Core Center of Instruct-ERIC
- Member of Instruct-ERIC Executive Committee and Council
Research Contributions:
- Developed in-cell NMR for studying proteins in their native environment
- Elucidated mechanisms of iron-sulfur cluster assembly in human cells
- Advanced structural vaccinology through antigen-antibody interaction studies
Technological Innovations:
- Fluorinated protein expression for 19F NMR in live cells
- Drug screening methodologies using real-time NMR
Collaborations & Impact:
- Coordinated European infrastructure projects (e.g., Instruct-ERIC)
- Contributed to meningococcal vaccine design via structural insights
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