Luca Digiacomo

Luca Digiacomo is a Tenure Track Researcher at Sapienza University of Rome, specifically within the Department of Molecular Medicine in the Faculty of Medicine. His research focuses on nanoparticle-protein interactions, with special emphasis on the biomolecular corona phenomenon and its applications in early cancer detection, particularly for pancreatic ductal adenocarcinoma. He teaches physics courses for medical and dental students while conducting cutting-edge research in nanomedicine diagnostics.

Dr. Digiacomo's educational background includes:

• Ph.D. in Life and Health Science from the School of Advanced Studies, Università di Camerino (2018)
• Laurea Magistrale in Physics of Matter from Università di Pisa (2014)
• Laurea Triennale in Physics from Università degli Studi di Catania (2011)
• Visiting Student at the Laboratory for Fluorescence Dynamics, University of California Irvine (2017)

Dr. Digiacomo's research centers on the biomolecular corona phenomenon - the layer of proteins that forms around nanoparticles when introduced into biological fluids. His work demonstrates how disease-specific patterns in this protein corona can serve as diagnostic biomarkers, particularly for pancreatic cancer. He has pioneered approaches to transform what was once considered a complication in nanomedicine into a powerful diagnostic tool. His research spans fundamental studies of protein-nanoparticle interactions to developing practical diagnostic applications with clinical relevance.

Analysis of Dr. Digiacomo's publications reveals a clear progression from basic research on protein corona formation to developing clinical diagnostic applications. His work shows increasing sophistication in leveraging personalized protein coronas for cancer detection, with recent publications focusing on translating these findings into practical blood tests. The research demonstrates strong interdisciplinary collaboration across physics, medicine, and engineering disciplines.

Dr. Digiacomo has led significant research projects including:

• "Early diagnosis of pancreatic cancer by biomolecular corona of graphene nanoflakes"
• "The protein corona of graphene oxide as a diagnostic tool for the early diagnosis and molecular staging of pancreatic ductal adenocarcinoma"

His teaching responsibilities encompass physics courses for first-year medical, dental, and biomedical laboratory techniques students across multiple programs at Sapienza University of Rome. He has extensive experience teaching physics to healthcare professionals, bridging the gap between fundamental science and medical applications.