معرفی
Lu Chen is an Assistant Professor at Temple University's Fox Chase Cancer Center, affiliated with the Cancer Epigenetics Institute Research Program specializing in Nuclear Dynamics and Cancer. Their lab focuses on RNA biology mechanisms underlying cancer and aging-related diseases. Key research areas include epigenetic regulation of telomerase, engineering senescence-resistant CAR-T cells, and developing CRISPR-based diagnostics.
Education includes a PhD in Biochemistry and Molecular Biology from the University of Kansas Medical Center (2013), postdoctoral training at Stanford University (2013–2019), and a BS from Wuhan University (2006). Honors include the NIGMS-MIRA Award (2023) and Stanford Cancer Institute Fellowship (2018).
The lab employs advanced techniques like icSHAPE-seq, CRISPR engineering, and single-molecule imaging. Current projects investigate telomerase regulation, RNA modifications, and translational therapies for degenerative diseases. Collaborations span structural biology, nanotechnology, and clinical oncology.
- Lab Team: Includes postdocs (Aldana Vistarop, Musinu Zakari), PhD students (Julia Hoopman, Alexander Morris), and undergraduate researchers.
- Grants: Active NIGMS-MIRA funding supports ongoing studies on RNA processing and cancer immortality.
- Awards: Recognitions for telomere research and contributions to understanding RNA biology.
Labs: Operates at Fox Chase Cancer Center (lab website: luchenlab.org). Active in mentoring with a focus on training early-career scientists in molecular oncology and RNA technologies.
