Louise M. Henderson

Louise M. Henderson, PhD, MSPH, is a Professor in the Department of Radiology at the UNC School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center. Her work focuses on cancer screening and prevention with an emphasis on comparative effectiveness research of imaging modalities and real-world screening evaluation.

• Academic Roles: Co-Leader, UNC Lineberger Cancer Epidemiology Research Program
• Key Projects: Carolina Mammography Registry, North Carolina Lung Screening Registry, NCI Cancer Screening Research Network (CSRN) ACCESS Hub

Her research evaluates the net benefits of cancer screening in population-based settings, integrating biomarkers for risk prediction and assessing new screening technologies. She leads two major registries tracking mammography and lung screening outcomes and serves as co-PI for the NCI-funded CSRN ACCESS Hub.

Recent publications highlight trends in lung cancer screening disparities, incidental findings in imaging, and optimizing breast cancer screening strategies for high-risk and elderly populations. Her work spans 2003–2025, with a focus on imaging effectiveness and equity in diagnostics.

• Scientific Awards:
  • NIH grant for Cancer Screening Research Network
  • $1.2 million ACS grant for statewide screening tracking
  • $1.76 million NCI grant for low-dose CT lung screening studies

Louise Henderson actively advises through collaborative research and grant-funded initiatives, emphasizing real-world screening implementation and policy impact. Her work bridges clinical radiology, epidemiology, and public health strategy.