معرفی
Lorenzo Sempere is an Assistant Professor in the Department of Radiology at Michigan State University (MSU) and a faculty member of the Precision Health Program. His research focuses on microRNA-based diagnostics and therapies for breast and pancreatic cancer. Dr. Sempere earned his Ph.D. in Genetics from the Geisel School of Medicine at Dartmouth, followed by postdoctoral training there. He previously held faculty roles at Geisel School of Medicine and Van Andel Research Institute.
His laboratory investigates translational approaches to cancer prevention and early detection, leveraging tools like 3D modeling, animal models, and high-content tissue analysis. Key areas include tumor heterogeneity, cancer-stroma interactions, and microRNA-regulated gene networks in disease progression.
Recent work emphasizes microRNA-21 and miR-10b as therapeutic targets, alongside innovations in intraductal ablation techniques and multimodal imaging agents. The lab's research bridges basic science and clinical applications, aiming to improve precision medicine strategies.
Despite his prolific output, no scientific awards or notable grants are explicitly mentioned in the provided texts. The Sempere Laboratory collaborates on projects involving nanomedicine, imaging technologies, and exosomal biomarkers, contributing to both academic and applied research.
