Lonnie Shea

Lonnie Shea, Ph.D., is the Steven A. Goldstein Collegiate Professor of Biomedical Engineering at the University of Michigan. His research focuses on regenerative medicine, immune engineering, and precision health, leveraging biomaterials and nanotechnology to address challenges in tissue regeneration, immunomodulation, and disease monitoring. He leads the Shea Lab, which develops synthetic microenvironments to study tissue formation, promote regeneration, and monitor disease progression.

Key research areas include islet transplantation for diabetes, nerve regeneration post-spinal cord injury, and strategies to modulate immune responses in autoimmune diseases, allergies, and cancer. His lab also pioneers diagnostic systems for early cancer detection and therapy monitoring using systems biology and biomaterial-based sensors.

Publications highlight advancements in nanoparticle therapeutics, engineered immune niches, and biomaterial scaffolds for disease surveillance. His work bridges engineering and medicine, with applications in translational therapies and precision diagnostics.