Lise Goltermann

Lise Goltermann serves as an Assistant Professor in the Department of Immunology and Microbiology within the Faculty of Health and Medical Sciences at the University of Copenhagen. Her research focuses on bacterial resistance mechanisms and novel antimicrobial strategies, particularly targeting Gram-negative pathogens like Pseudomonas aeruginosa and Escherichia coli. She maintains an active laboratory investigating peptide-nucleic acid therapeutics and biofilm-related antimicrobial tolerance.

Her research interests center on antibacterial resistance evolution, with specific emphasis on ribosomal mutations, lipopolysaccharide biology, and the catalytic functions of biofilm matrices. Dr. Goltermann's work bridges molecular microbiology and therapeutic development, particularly exploring how peptide-PNA conjugates overcome bacterial membrane barriers to deliver antisense activity. She investigates both fundamental resistance mechanisms and translational applications for multidrug-resistant pathogens.

Analysis of her publication record (2017-2024) reveals consistent focus on bacterial resistance mechanisms, with increasing emphasis on peptide-PNA therapeutics and biofilm matrix functions. Her work demonstrates strong interdisciplinary connections between molecular microbiology, chemical biology, and clinical infectious disease research, particularly addressing challenges in Gram-negative pathogen treatment.

Dr. Goltermann maintains active collaborations across multiple institutions, evidenced by co-authorship with researchers from diverse specialties including clinical microbiology (Johansen HK), chemical biology (Nielsen PE), and biofilm research (Tolker-Nielsen T). Her work has generated significant scientific impact with multiple highly-cited publications and patent references.