معرفی
Lingjuan Hong is an Associate Research Scientist in the Department of Genetics at Yale School of Medicine. She holds a PhD from Zhejiang University (2015). Her research focuses on genetic mechanisms underlying cardiovascular development, hypertension, and neurovascular injury, with a particular emphasis on transcription factors and signaling pathways.
Key research interests include the role of PRDM6 in heart development and hypertension pathogenesis, GPR124 in vascular inflammation and repair, and the molecular basis of leukocyte-endothelial interactions in neurovascular disorders. Her work integrates systems biology approaches with experimental models to explore gene regulation in disease contexts.
Recent studies highlight discoveries such as PRDM6's role as a master regulator of renin-producing cells and its link to hypertension, as well as GPR124's contributions to pericyte migration during ischemic injury. These findings bridge basic science and translational medicine.
Publications span topics from CRISPR-based DNA repair optimization to neuroprotective drug design for Alzheimer’s disease. Hong collaborates across disciplines, leveraging genetic, pharmacological, and imaging tools to address complex biological questions.
