Linghua Wang

Dr. Linghua Wang is a tenured Associate Professor in the Department of Genomic Medicine, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center. She also holds a dual appointment as a Regular Member at the MD Anderson UTHealth Houston Graduate School of Biomedical Sciences. Dr. Wang leads the Computational Biology Laboratory, which has grown to 17 members since its inception in 2017.

Dr. Wang specializes in computational biology, cancer genomics, and immuno-informatics, with expertise in deep profiling of the tumor ecosystem at single-cell resolution. Her research focuses on three primary areas: the transition from premalignant lesions to invasive cancer, the evolution of metastasis, and the dynamic response to anti-cancer therapies and development of therapeutic resistance. She leverages cutting-edge single-cell and spatial multi-omics technologies combined with advanced bioinformatics tools for novel discovery.

Dr. Wang's publication portfolio demonstrates significant impact in cancer research, with over 120 publications including high-profile papers in Nature, Nature Medicine, Cancer Cell, and Cancer Discovery. Her work spans computational biology, tumor microenvironment analysis, and translational applications for cancer detection and treatment.

• Emil Frei, III Award for Excellence in Translational Research
• David M. Livingston Collaboration Award
• Sabin Fellow Award

Dr. Wang maintains an active research program with substantial funding from the National Cancer Institute (R01, U01), Cancer Prevention and Research Institute of Texas (CPRIT IIRA), Break Through Cancer Foundation, Andy Sabin Family Foundation, and MD Anderson Cancer Center Moon Shots Program. Her lab follows a collaborative, team-based strategy to tackle cancer research challenges, fostering a supportive environment for trainees and researchers.

The Computational Biology Laboratory is actively seeking highly motivated graduate students interested in computational approaches to cancer research. Dr. Wang serves as a Scientific Editor for 'Cancer Discovery' and participates in NIH/NCI grant review panels, demonstrating her leadership and recognition in the field.