معرفی
Lei Wang is an Assistant Professor of Bioengineering (College of Engineering) and Biology (College of Science) at Northeastern University since January 2024. Her research focuses on mammalian synthetic biology, microfluidics, and organ-on-a-chip technology for biomedical applications.
- Ph.D. in microfluidics and biosensors
- Postdoctoral training in genetically programming hiPSCs at MIT Biological Engineering Department
Her research interests include:
- Designing genetically encoded microRNA sensors for live cell-state monitoring
- Bioengineering cell fate transitions for regenerative medicine and cancer therapy
- Developing organ-on-a-chip models with patient-specific hiPSCs
- Creating ultra-sensitive biosensors for pathogen detection
- Integrating synthetic biology with microfluidics
- Advancing automated, logic-driven cellular differentiation
Her recent publications show a strong trend in synthetic biology tools for cell fate engineering, with applications in cancer therapy, infectious disease diagnostics, and tissue modeling. Notable work includes programmable microRNA sensors for cell state transitions and microfluidic systems for dynamic hypoxia studies.
Scientific Awards:
- NIH Trailblazer Award (2024): $673,600 for programmable RNA sensors in targeted therapies
Additional Contributions:
- Co-inventor on patents for multi-input miRNA sensing and capacitive pathogen detection
- Developed tumor-on-chip models and ultra-sensitive biosensors
- Research supported by collaborations with MIT and Northeastern labs
- Lei Wang Lab focuses on humanized disease models and cell fate engineering
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