معرفی
Dr. Leah Seebald is an Assistant Professor of Chemistry at Haverford College, specializing in chemical biology and organic synthesis. Her research focuses on designing chemical tools to study RNA-protein interactions and bacterial glycosylation pathways, with applications in antimicrobial development and structural biology.
- University: Haverford College
- Academic Rank: Assistant Professor
- Research Area: Chemical Biology
- Email: lseebald@haverford.edu
The Seebald lab investigates the reactivity of 2H-azirine functional groups in biological probes and covalent inhibitors. Using techniques like organic synthesis, chromatography, and NMR spectroscopy, the group develops tools for studying RNA-protein interactions and bacterial glycosylation mechanisms.
Recent publications highlight her work on paramagnetic NMR probes, azirine-based inhibitors for phosphoglycosyl transferases, and bioorthogonal chemistry applications. The lab also explores computational modeling of membrane partitioning and diversity-oriented synthesis of bioactive molecules.
Students in the Seebald lab, including Carrie Everett, Joseph DeRosa, Sarah McNamara, and others, have presented at events like the KINSC poster session and ISCC convention. Hannah Harrison and Xinnuo Chen received honorable mentions at ISCC 2024.
