Laurent Calvier

Laurent Calvier is a tenure-track Assistant Professor at UT Southwestern Medical Center's Department of Neurology, focusing on vascular inflammation mechanisms across chronic diseases. His research bridges cardiovascular biology and neuroimmunology through studies on the Reelin signaling pathway.

• PhD from INSERM (2012)
• Postdoctoral training at Hannover Medical School (pulmonary hypertension) and UT Southwestern (chronic inflammation)
• Co-founder of Reelin Therapeutics for developing anti-Reelin antibodies

His work explores vascular inflammation in atherosclerosis, Alzheimer's disease, multiple sclerosis, and rheumatoid arthritis, with recent publications in Science Immunology and Cell Reports showing Reelin's role in endothelial dysfunction. He has secured NIH funding and holds a patent for Reelin-targeted therapies.

Scientific awards include competitive fellowships from DFG, FEBS, and Keystone, along with grants from ESAC and Harrington. His research team investigates Reelin's therapeutic potential using preclinical models across multiple inflammatory disease contexts.