معرفی
Laleh Majlessi is an Associate Professor at the Institut Pasteur, where her research focuses on the immunological interactions between mycobacteria—particularly Mycobacterium tuberculosis—and the host immune system. Her work bridges fundamental immunology and translational vaccinology, with a focus on developing novel vaccine strategies against tuberculosis and emerging infectious diseases.
Her research interests include:
- Innate and adaptive immunity to mycobacterial infections
- Immunogenicity of type VII secretion system substrates
- Development of lentiviral vector-based vaccines
- Mucosal immunity and intranasal vaccination
- Immune responses to SARS-CoV-2 and HPV-induced cancers
Her recent publications highlight a strong trend toward innovative vaccine platforms, particularly using lentiviral vectors to induce robust and targeted T-cell immunity against infectious agents and cancers. These studies often involve preclinical models and emphasize mucosal delivery and immune memory.
Scientific awards she has received include:
- Jean-Marie Dubert Prize for best PhD in immunology (1994)
- Georges, Jacques and Elias Canetti Prize (2016)
Dr. Majlessi has been actively involved in advising and collaborative research, particularly in the development of vaccine candidates. While specific grant details are not mentioned, her extensive publication record in high-impact journals suggests sustained funding and leadership in immunology and vaccinology. She collaborates with prominent scientists such as Pierre Charneau and Hélène Strick-Marchand.
She is associated with research teams focused on:
- Modeling SARS-CoV-2 infection in humanized mouse models
- Integrated mycobacterial pathogenomics
- Development of lentiviral immunotherapies
