معرفی
Labib Mamun serves as a Research Specialist at Colgate University within the Williams Lab, focusing on neuroinflammation mechanisms in the central nervous system (CNS). His work examines interactions between extended endocannabinoid receptors and HIV infection of the brain, alongside blood-brain barrier permeability dynamics.
Education
- BSc in Neuroscience, Colgate University
Mamun's research centers on neuroimmune interactions in HIV pathogenesis, particularly how endocannabinoid signaling modulates neuroinflammation and blood-brain barrier integrity during viral infection. His investigations address critical gaps in understanding substance abuse comorbidities with neuroHIV, utilizing advanced in vitro and in vivo models to dissect cellular mechanisms.
His 15 most recent publications (2023-2025) reveal strong thematic continuity in neuroimmunology and HIV therapeutics, with dominant threads including cocaine/cannabis impacts on antiretroviral pharmacokinetics, spatial lipid heterogeneity in SIV models, and blood-brain barrier cell-type-specific drug metabolism. Key methodological approaches involve TRAP technology, multi-omics integration, and primate neuroimaging.
Scientific Awards
- William E. & Nellie K Edmonston Neuroscience Award, Colgate University
- Johns Hopkins Neuro-HIV Comorbidities Scholar, Johns Hopkins School of Medicine
- John A. Golden ’66 Fellow, Colgate University
- Office of Undergraduate Studies Scholar, Colgate University
Mamun has presented at major venues including NIH NCCIH meetings and Johns Hopkins Hospital symposia, with recent work on TRAP technology in rat sensory behavior and endocannabinoid receptor expression in HIV-infected microglia. He operates within the Williams Lab's collaborative framework investigating neuroimmune communication in HIV/substance abuse contexts, though no student advising or grant details are publicly documented.
