
Kurt Wüthrich
استاد · Nuclear Magnetic Resonance Spectroscopy
Irell and Manella Graduate School of Biological Sciencesمعرفی
Kurt Wüthrich is a renowned Professor of Structural Biology at The Scripps Research Institute (La Jolla, CA), a Professor of Biophysics at ETH Zurich (Switzerland), and a Distinguished Senior Professor at ShanghaiTech University (China). He holds the Cecil H. and Ida M. Green Chair at Scripps and has joint appointments in the Department of Chemistry and the Skaggs Institute for Chemical Biology. His research focuses on nuclear magnetic resonance (NMR) spectroscopy of biological macromolecules, particularly G protein-coupled receptors (GPCRs) and aging-related healthcare. Wüthrich pioneered NMR-based protein structure determination and developed the TROSY method for large biomolecular assemblies.
Education:
- Lizentiat in Chemistry, Physics, and Mathematics, University of Bern
- Ph.D., Chemistry, University of Basel
- Postdoctoral Training: UC Berkeley (USA) and University of Basel
Research Interests: Wüthrich’s work spans NMR methodology, protein dynamics, and structural biology. Recent projects include GPCR signaling mechanisms, sarcopenia’s impact on healthspan, and transmembrane signal transfer. His lab at ShanghaiTech explores GPCR structure-function relationships, while Scripps collaborations address aging-related health challenges.
Awards: A Nobel laureate (2002), Wüthrich has received the Kyoto Prize (1998), Marcel Benoist-Preis (1992), and numerous honorary doctorates. His contributions to NMR and structural biology are globally recognized.
Labs: Active research groups at ETH Zurich, Scripps, and ShanghaiTech collaborate on NMR-driven drug discovery and aging studies. Wüthrich’s laboratories emphasize interdisciplinary approaches to biomedical challenges.
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