Kristian Gurashi

Kristian Gurashi is a Postdoctoral Researcher in the Mead Group at the University of Oxford, focusing on Normal and Malignant Haematopoietic Stem Cell Biology. His work integrates multiomic approaches to study myeloid malignancies such as chronic myelomonocytic leukemia (CMML), myelofibrosis, and myelodysplastic syndromes (MDS).

• Key Research Areas:
  • Haematopoietic Stem Cell Biology
  • Myeloid Malignancies
  • Single-Cell Genomics
  • Organoid Modeling
  • Precision Medicine
  • Immune Suppression Mechanisms

His recent publications highlight the application of single-cell sequencing, spatial transcriptomics, and organoid models to dissect clonal evolution, microenvironmental interactions, and therapeutic resistance. Notable trends include studies on TP53 mutations, JAK2 allelic burden, and MDMX expression as prognostic and therapeutic indicators. His work also explores inflammatory signaling and aberrant cell communication in disease progression.