معرفی
Kounosuke Watabe is a Professor in the Department of Cancer Biology at Wake Forest University School of Medicine. He serves as Associate Director of Education and Training and Shared Resources at the Wake Forest Baptist Comprehensive Cancer Center.
- Research focus on tumor microenvironment, cancer stem cells, and non-coding RNAs in breast and prostate cancers
- Published over 150 papers with an h-index of 51
- Director of T32 Translational Oncology Training Program and R25 cancer research promotion program
Research Interests:
The lab investigates molecular mechanisms of tumor metastasis, particularly in breast and prostate cancers. Key areas include:
- Tumor microenvironment interactions in bone and brain metastasis
- Non-coding RNA regulation of cancer progression
- Fatty acid metabolism in tumor initiation
- Cancer stem cell dynamics
- Development of immunotherapies to control metastasis
Scientific Awards:
- Molecule of the Year (2011) by ISMCBBPR
- Top 100 Science Discovery (2013) in Discover Magazine
Research Trends:
Recent publications emphasize exosomal miRNAs (2021), nicotine's role in metastasis (2021), and multi-omics analysis of brain metastasis outcomes (2020). Earlier work established fatty acid synthase as a therapeutic target (2005-2008) and clarified microRNA regulation of cancer stem cells (2009-2013).
Leadership & Funding:
He has served on federal grant review panels and led team science projects across three institutions. His research has received continuous NIH and federal funding.
Labs & Collaborations:
The Kounosuke Watabe Lab collaborates with Wake Forest Institute for Regenerative Medicine (WFIRM), Maya Angelou Research Center for Healthy Communities, and Public Health Sciences departments.
