Konstantin Sparrer

Prof. Dr. Konstantin Sparrer is a Group Leader at the Institute of Molecular Virology, Ulm University Medical Center, and affiliated with the German Center for Neurodegenerative Diseases (DZNE). His research investigates molecular mechanisms linking viral infections and neuroinflammation to neurodegenerative disorders like Alzheimer's disease, utilizing cerebral organoids, primary cell cultures, and mechanistic studies of viral immune evasion.

His work spans:

• Neurotropic Viruses: Dissecting viral impact on inflammation, proteostasis, and cellular energy homeostasis.
• Innate Immunity: Studying monogenic inflammatory diseases to understand neuropathology and protective immune responses.
• Therapeutic Development: Designing neurotropic viral vectors for gene therapy and screening human peptidomes for anti-inflammatory peptides.

Dr. Sparrer's lab focuses on optimizing viral glycoproteins for targeted gene delivery and exploring immunometabolic pathways in neurodegeneration. He collaborates internationally via platforms like Swarm Learning Hub and contributes to virology societies (e.g., Gesellschaft für Virologie).