معرفی
Klaus Pfeffer is a Full Professor (W3/C4) and Director of the Institute of Medical Microbiology and Hospital Hygiene at Heinrich Heine University Düsseldorf, where he leads research on antimicrobial immunity. His group focuses on IFN-induced GTPases (mGBPs) and their role in combating intracellular pathogens like Toxoplasma gondii, Listeria, and Chlamydia using molecular biology, confocal microscopy, and genetically modified mouse models. Additional research examines lymphotoxin receptor signaling in immune defense and microbiome analysis via whole-genome sequencing.
Education & Career:
• Medical degree (1987) and Dr. med. (1988) from University of Ulm
• Habilitation in Microbiology/Immunology (1996) at Technical University of Munich
• Full professorship at HHU Düsseldorf since 2002
Key Research Areas:
• Molecular mechanisms of IFN-induced GTPases in pathogen control
• Lymphotoxin β receptor signaling in infection defense
• Jak2 kinase in innate immunity
• Microbiome dynamics in hematological diseases
Major Awards:
• Gottfried Wilhelm Leibniz Prize (DFG, 2004)
• Erdeniin Ochir Medal (Mongolia, 2018)
• Honorary Professorship (Mongolian National University, 2014)
Leadership & Projects:
• Speaker of Jürgen Manchot Graduate School "Molecules of Infection"
• Principal Investigator in DFG Research Units (e.g., RTG 1949, FOR 729)
• Current projects include functional analysis of GBPs in chlamydia defense and LTβR-mediated immunity
