Kim Carlyle Worley

Kim Carlyle Worley is a Professor at Baylor College of Medicine, serving as Chair of the Faculty Senate and Vice Chair for Research Affairs in the Department of Molecular and Human Genetics. Her research focuses on genomic data analysis, including roles in major projects like the Human Genome Project, Human Microbiome Project, and comparative genomics across species. She leads initiatives such as the All of Us data science training program, ClinGen variant curation for inherited retinal diseases, and Alzheimer’s structural variant analysis.

Education:

• PhD in Molecular and Human Genetics, Baylor College of Medicine (1993)
• Postdoctoral Fellowship in Bioinformatics, Baylor College of Medicine (1997)
• BS in Chemical Engineering, Massachusetts Institute of Technology (1984)

Research Interests: Dr. Worley’s work bridges computational and experimental genomics, emphasizing genome assembly, variant analysis, and clinical translation. Current projects include leveraging large-scale genomic data for precision medicine (All of Us Program), curating disease-associated variants, and applying novel sequencing technologies to diagnose undiagnosed disorders through the Undiagnosed Diseases Network.

Awards & Roles:

• Deputy Editor (honored in awards section)
• Lead investigator in multiple NIH-funded consortia
• Strategic advisor for genomic data platforms like Consultagene

Grants & Labs: Active in securing and managing grants for genomic infrastructure projects. Leads the Baylor Undiagnosed Diseases Center’s sequencing analysis team and collaborates with global networks to advance genomic medicine.