Kevin R. Siebenlist

Dr. Kevin R. Siebenlist is an Associate Professor Emeritus in the Department of Biomedical Sciences at Marquette University's College of Health Sciences. He holds a Ph.D. in Biochemistry from the Medical College of Wisconsin (1984) and completed postdoctoral training in hemostasis at The Blood Center of Southeastern Wisconsin and Sinai Samaritan Medical Center. His research focuses on hemostasis, particularly fibrinogen structure and function, factor XIII activity, and thrombin interactions.

• Education:
  • B.S., Chemistry, University of Wisconsin-Milwaukee (1977)
  • Ph.D., Biochemistry, Medical College of Wisconsin (1984)
  • Postdoctoral Fellowships in Hemostasis (1984–1987)

Research Interests: Dr. Siebenlist studies fibrinogen's role in blood clotting, including its structural variations (e.g., γ' chain function), factor XIII-mediated crosslinking, and thrombin binding dynamics. His work explores how these molecular interactions influence clot formation, stability, and thrombotic risks.

Publications reflect contributions to understanding fibrinogen mutations (e.g., Fibrinogen Cedar Rapids), factor XIII activity, and fibrinolysis regulation. He has authored/co-authored over 50 peer-reviewed articles and abstracts, with recent work focusing on α2-antiplasmin incorporation into fibrinogen and Factor XIII variants' crosslinking activity.

• Scientific Awards/Honors:
  • Phi Beta Kappa
  • Phi Kappa Phi
  • Member, American Association for the Advancement of Science
  • Member, International Fibrinogen Research Society
  • Member, 'Scientist Panel' of Index Copernicus International

Teaching and Curriculum: Dr. Siebenlist teaches courses in biochemistry, organic chemistry for health sciences, and pre-medical/pre-dental advising. He contributes to programs like the Undergraduate Summer Research Program and the Pre-Dental Post-Baccalaureate Program.

Lab Affiliations: Collaborates with the Fibrinogen Research Laboratory at The Blood Center of Southeastern Wisconsin (Dr. Mosesson) on in vitro fibrinogen expression systems and mutagenesis studies.