معرفی
Kerstin Wendt is an Associate Professor in the Department of Cell Biology at Erasmus MC, where she conducts active research in chromatin dynamics, cohesin biology, and gene regulation. Her work integrates molecular genetics, live-cell imaging, and genomic technologies to understand fundamental processes in cell division and developmental disorders.
Her research focuses on the mechanisms of sister chromatid cohesion, chromatin organization, and the role of cohesin in health and disease. Key areas include CRISPR-based functional genomics, spatial chromatin architecture, and the molecular basis of Cornelia de Lange Syndrome. She employs advanced techniques such as live-cell imaging, next-generation sequencing, and optical imaging to probe dynamic chromatin behaviors.
The recent publications highlight a strong trend in understanding how transcriptional machinery like RNA Polymerase II influences 3D genome reorganization after mitosis, and how cohesin regulators impact chromatin structure. Her work bridges basic cell biology with clinical genetics, contributing to both mechanistic insights and disease modeling.
Dr. Wendt collaborates extensively with researchers across disciplines, as evidenced by her co-authorship on studies involving chromatin imaging, gene expression, and developmental disorders. While specific advising roles are not listed, her senior authorship indicates mentorship of junior researchers and students.
Her lab or research team likely focuses on genomic stability, chromatin dynamics, and molecular mechanisms of developmental syndromes, utilizing cutting-edge cellular and molecular tools to address fundamental questions in epigenetics and cell biology.
