معرفی
Dr. Kerri Kobryn is an Associate Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. She holds a BSc (Honours) in Genetics from the University of Western Ontario and a PhD in Genetics from the University of Glasgow. Her research focuses on the biochemistry and molecular biology of the Lyme disease spirochete Borrelia burgdorferi, particularly studying the enzyme ResT responsible for forming its unique hairpin telomeres. This work aims to develop Borrelia-specific therapies targeting telomere maintenance mechanisms.
Research interests include understanding ResT's role in DNA replication, identifying accessory factors for telomere formation, and investigating genome linearity origins by introducing ResT into E. coli. Current projects explore biochemical characterization of Borrelia's RecA protein and DNA unwinding activities of ResT. Dr. Kobryn accepts applications for NSERC Undergraduate Student Research Awards and Honour students.
Her lab's contributions span telomere resolvase mechanisms, DNA topology effects on enzyme activity, and structural-functional relationships in bacterial pathogens. Collaborative efforts address Lyme disease pathogenesis and antimicrobial drug development strategies targeting unique Borrelia biology.
