Anders Hofer

Anders Hofer is an Associate Professor and Docent in Medical Biochemistry at Umeå University's Department of Medical Biochemistry and Biophysics, serving as Director of Studies. His research focuses on nucleotide metabolism in pathogens and mammalian cells, with an emphasis on enzymes like ribonucleotide reductase and nucleoside kinases. His work targets pathogens such as Trypanosoma brucei (African sleeping sickness), Giardia intestinalis, and Borrelia burgdorferi (Lyme disease), aiming to develop drugs exploiting their metabolic vulnerabilities. His lab employs techniques like GEMMA analysis, mass photometry, and nucleotide quantification methods. Recent grants include a three-year strategic research grant from the Medical Faculty in 2023.

Key projects include studying nucleotide salvage pathways in pathogens and developing adenosine analogues as antiparasitics. Collaborations span structural biology, enzymology, and drug discovery. His work addresses antibiotic resistance by targeting unique pathogen features.