Kelly Hogan

Kelly Hogan, Ph.D., is an Assistant Research Professor in the Department of Biochemistry and Molecular Biology at Pennsylvania State University. She is affiliated with the McReynolds Lab and specializes in placenta biology, pregnancy metabolism, cellular senescence, and immunomodulation. Her research focuses on CD38 enzyme mechanisms, NAD+ metabolism, and age-related pathologies, with applications to placental health and environmental health impacts on pregnancy.

Key research interests include understanding how cellular senescence and inflammatory pathways influence placental function during pregnancy, particularly in response to infections like Group B Streptococcus. She also explores metabolic disruptions in aging and diseases, leveraging biochemistry and mass spectrometry imaging techniques. Her work bridges basic science and translational research, addressing both fundamental biological questions and clinical implications in maternal-fetal medicine and immunology.

Her publications highlight advancements in senolytic drug development, CD38’s role in immune regulation and viral pathophysiology (e.g., COVID-19), and the interplay between environmental exposures and pregnancy outcomes. Notably, her team investigates how factors like air pollution interact with social determinants of health to affect vulnerable populations.

No scientific awards are explicitly mentioned. Her research group collaborates across disciplines, with funding interests likely tied to NIH/NIGMS or similar grants, though specific grants are not listed here. The McReynolds Lab serves as a central hub for her experimental investigations.