Keith J. Stine

Keith J. Stine is a Professor and Department Chair in the Department of Chemistry and Biochemistry at the University of Missouri–St. Louis (UMSL), within the College of Arts and Sciences. He has been a faculty member since 1990 and plays a significant leadership role in the university, having previously served as Chair of the Faculty Senate and University Assembly.

His educational background includes a BS from Fairleigh Dickinson University and a PhD from MIT, followed by postdoctoral training at UCLA.

Dr. Stine's research is centered on modified surfaces and nanostructures, particularly nanoporous gold, with applications in bioanalytical chemistry, sensors, immunoassays, and separations. He investigates surface immobilization of proteins, lipid monolayers as cell membrane models, and carbohydrate-protein interactions. His work integrates electrochemical methods such as impedance spectroscopy and cyclic voltammetry with advanced characterization techniques like SEM, TEM, AFM, and gas adsorption analysis.

The 15 most recent publications highlight a strong trend in the development and application of nanostructured materials, especially nanoporous gold, for drug delivery, biosensing, and glycan synthesis. There is a clear interdisciplinary focus spanning materials science, electrochemistry, glycochemistry, and biomedical applications, often in collaboration with the Demchenko lab at Saint Louis University.

While no formal scientific awards are listed in the provided text, his extensive publication record in high-impact journals reflects significant scholarly contributions.

Dr. Stine actively mentors students and researchers, with numerous co-authors on recent papers indicating a vibrant research group. He has been involved in projects related to grants in nanomaterials, bioanalytical chemistry, and carbohydrate synthesis, though specific grant details are not provided. His research contributes to both fundamental science and translational applications in diagnostics and therapy.

His laboratory focuses on the synthesis and characterization of functional nanostructures, particularly for biomedical applications. The team explores hierarchical architectures in nanoporous metals, electrochemical biosensors, and automated carbohydrate synthesis, working at the intersection of chemistry, materials science, and biology.