Keith Abrams

Keith Abrams is an Honorary Professor at the University of York's Centre for Health Economics and Partner/ Director at Visible Analytics. Previously, he held a Professorship in Medical Statistics at the University of Leicester, leading the Biostatistics Research Group. His work focuses on methodological advancements in Health Technology Assessment (HTA), including Bayesian statistical methods for clinical trials, evidence synthesis, natural history modeling for rare diseases, and analysis of large-scale electronic health records (EHR). He has extensive involvement with UK regulatory bodies like NICE (National Institute for Health and Care Excellence), serving on multiple committees including the Technology Appraisals Committee and Diagnostics Advisory Committee. His methodological contributions are supported by grants from ESRC, MRC, and industry partnerships.

Research interests emphasize statistical innovations for HTA, particularly in oncology, rare diseases, and multimorbidity. He has authored/co-authored seminal books on meta-analysis, Bayesian approaches, and evidence synthesis in healthcare. Recent work includes evaluating surrogate endpoints in Alzheimer's disease and prostate cancer trials, analyzing pandemic impacts using EHR data, and developing natural history models for Duchenne Muscular Dystrophy (DMD). His cross-disciplinary collaborations bridge academia, industry, and policy, addressing evidence-based decision-making challenges in healthcare.

Key accolades include NIHR Senior Investigator Emeritus status, Royal Statistical Society Fellowship, and Chartered Statistician designation. His research spans 20+ years, with over 200 peer-reviewed publications and methodological guidelines influencing international HTA practices.